ASM Data

New data on the speed, accuracy and advantages of the Accelerate Pheno system

Children’s Healthcare of Atlanta & University of Texas Southwestern Medical Center -

Performance of a Novel System for Rapid Identification and Susceptibility Testing Directly from Positive Pediatric Blood Cultures

M. Gonzalez, J. Vong, R. Jerris, and E. McElvania TeKippe

From the data
  • “Overall ID sensitivity of 96.0% and specificity of 99.1%”
  • “Antibiotic susceptibility testing resulted in an overall essential agreement of 96.2% and categorical agreement of 94.8%”

  • Geisinger Health & Geisinger Medical Center -

    Clinical Performance of an Innovative System for Rapid Microbe Identification & Antimicrobial Susceptibility Testing from Positive Blood Cultures, Including a Unique Monomicrobial Designation

    D. Hernandez, K. Rygalski, A. Styer, M. Updike, and D.M. Wolk

    From the data
  • “In our data set, the Accelerate PhenoTest™ BC kit's monomicrobial call was made for 75% of samples with 100% PPV”
  • “Samples where the call was made had 99.4% sensitivity, with a specificity of 100%”
  • “On average, AST results would be returned 38.5h sooner than reference AST”

  • Karolinska University Hospital & Karolinksa Institute -

    A Novel System for Microbial Identification and Susceptibility Testing Directly from Clinical Blood Culture Samples

    P. Luthje, M. Ullberg, V. Ozenci

    From the data
  • “Categorical agreement with microbroth dilution for ceftazidime, piperacillin-tazobactam and aztreonam increased to >90% when applying [latest software]”

  • St. John Hospital & Medical Center -

    Evaluation of an Automated Platform for Rapid Identification and Antibiotic Sensitivity Testing of Bacteria Directly from Positive Blood Culture Bottles

    R. Nudell, K. Belkowski, J. Gay, D. Downey, T. E. Schutzbank

    From the data
  • “For AST, overall Essential Agreement (EA) was 97.4% and Categorical Agreement (CA) was 96.2% when compared to VITEK®2 results”
  • “...decrease in time to ID and AST by an average of 26.7 hours and 43.8 hours, respectively”

  • Texas Children's Hospital & Baylor College of Medicine -

    Evaluation of the Accelerate Pheno™ system for the Rapid Identification and Susceptibility of Gram-Negative Rods from Positive Blood Cultures

    C. Johnson Ph.D., A. Davis, R. Riordan, A. Rivera-Acosta, M. Castillo De Tunon, J. Dunn Ph.D. and P. Revell, Ph.D.

    From the data
  • “Results showed 97.1% agreement in ID between the Accelerate Pheno™ system and conventional methods”
  • “AST results showed an overall essential agreement of 93.8% and overall category agreement of 94.5%”
  • “AST results were available on average 55 hours earlier with the Accelerate Pheno™ system compared to traditional methods”

  • University of Chicago -

    Use of Accelerate Pheno™ system for the Identification and Susceptibility (ID/AST) of Pathogens in Positive Blood Cultures and Impact on Time to Results and Workflow

    V. Tesic, B. Hill, N. Love, S. Boonlayangoor, A. Charnot-Katsikas, K.G. Beavis

    From the data
  • “Time to identification and susceptibility was reduced by 23.5 and 41.9 hours, respectively; hands-on time was reduced by 32 min”
  • “Overall [identification] sensitivity and specificity was 95.6% and 99.5%”
  • “[Overall] essential agreement was obtained in 94.8% and categorical agreement in 95%”

  • University of Houston College of Pharmacy, CHI Baylor St. Luke's Medical Center & Baylor College of Medicine -

    Accelerate PhenoTest™ BC Kit vs. Conventional Methods for Identification and Antimicrobial Susceptibility Testing of Gram-positive Bloodstream Isolates: Implications for Antimicrobial Stewardship

    A. Sofjan, B. Casey, B. Xu, J. Amadio, A. Restrepo, M. Alam, K. Garey

    From the data
  • “84% of patients had at least one intervention possible”
  • “Targeted/active therapy could be initiated a median of 43 hours earlier (IQR, 32-66 hours)”
  • “Unnecessary antibiotics could be stopped a median of 37 hours earlier (IQR, 20-60 hours)”

  • University of Texas Southwestern Medical Center, Children's Medical Center & Emory University Hospital -

    Evaluation of the Accelerate Pheno™ system: Results of a Large Academic Medical Center

    C. Bittencourt, E. McElvania TeKippe, D. Cavuoti, Joseph D. Lutgring, E. Burd, R. Hollaway

    From the data
  • “Correctly identified 106 of 112 on-panel organisms and showed: - Sensitivity: 94.5% - Specificity: 99.1%”
  • “Categorical agreement: 94% - Very major errors: 1.2% - Major errors: 0.7% - Minor errors: 5%”
  • “Identification and antimicrobial susceptibility results were an average of 36 and 44 hours faster than SOC”
  • Recap of the live & unscripted Q & A session from their experiences with the Accelerate Pheno system

    Christa Pardue, MBA, MT(AMl)
    Director of Laboratory Services,
    University Healthcare System, Augusta, GA

    Margie Morgan, PhD
    Associate Professor of Pathology, Scientific Director,
    Microbiology, Cedars-Sinai, Los Angeles, CA