BACcel RUO

Benefits of the BACcel System

Rapid results

Completes single-cell microbiology analysis, direct from specimen without prior culturing and colony isolation. ID available in 1 hour, AST within 6 hours*.

Easy to use

Assay set up is simple and quick. The BACcel system automates all process steps once sample is inserted into standard cassette.

Supports broad range of sample types

Employs advanced methods for specimen preparation with live organism extraction, concentration, and capture.

Reproducible results

Automation steps reduce errors and standardize processing

BACcel System Components and Operation

The BACcel instrument

The instrument automatically exchanges test solutions, acquires time-lapse images and applies sophisticated image analysis to measure the responses of each individually identified microbial cell. It applies expert rule sets to interpret data and report results in standard clinical terminology. Core components include:

 

_ANW7818Disposable analyzer cassette and reagent source plate kit

The cassette has 32 independent flowcell channels, wherein fluid exchanges provide different test conditions, exposing the captured cells to different test solutions. The flowcell is the central element in the BACcel system. It is a hollow channel that guides flow from an inlet port, through the channel, into an outlet port. It has transparent top and bottom covers so the microscope can view its inner surfaces. Microbial cells from a sample attach inside the bottom cover. Fluid exchanges provide different test conditions, exposing the captured cells to different test solutions.

_ANW8967Automated fluidics

A computer-controlled micropipetting robot exchanges reagents according to program.

300x450Automated microscopy

A computer-controlled microscope is the heart of the instrument. It scans a cassette placed on its stage, changes imaging modes, and acquires digital images according to program.

videoAutomated image analysis 

Highly sophisticated, proprietary image analysis software provides state-of-the-art cell tracking and measurement of each cell’s responses to different tests. Tracking each cell at all times, it measures changes in growth rates, shapes, and other properties that indicate the effects of different tests. It finishes by constructing a statistical profile of each sub-population of cells and interpreting results using expert rules. Please click here to see this process in action.

* Typical results, although certain organisms could require up to 8 hours.