Patient Case: 76-year-old female patient with pancreatic cancer

MD Anderson Cancer Center

Cancer center in Houston, TX

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ICU De-Escalation Patient

76-year-old female patient with pancreatic cancer with liver and lung metastases and a history of COPD presents to ED with fever and worsening abdominal pain after an IR biopsy of liver lesion. She was given pain medication but became lethargic and began to have respiratory distress. Blood cultures were drawn, and she was admitted to the ICU.

Empiric therapyVancomycin and cefepime
ID/AST methodAccelerate PhenoTest® BC kit
ID resultEscherichia coli
AST resultsHighly susceptible profile
Therapy changeDe-escalated to ceftriaxone
Time to AST results∼7h post +BC with Accelerate PhenoTest BC kit

Case Discussion

The patient was transferred out of the ICU 3 days after admission and was discharged home on oral ciprofloxacin the next day.

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